iHealth T2D Study

iHealth T2D Study

`In recent decades, India has witnessed a rapidly exploding epidemic of Diabetes. Indeed India today has the second largest number of people with Diabetes in the world. The prevalence of Diabetes in urban India especially in large metropolitan cities has increased from 2% in 1970’s to 20% at present and the rural areas are also fast catching up. Type 2 Diabetes is the fifth leading cause of death worldwide and a major contributor to development of coronary heart diseases, stroke, vascular disease and kidney diseases. Thus, there is an urgent need for strategies to prevent or at least slow down the emerging epidemic of diabetes.

Diabetes is preventable!!!

Large, high-quality clinical trials show that modest changes to diet and physical activity through a structured, 1 year lifestyle intervention can reduce the incidence of T2D by more than 50% in people at high risk of T2D. . Many European studies show that intensive lifestyle modifications, maintaining reasonable body weight, being physical active by including adequate exercise is associated with reduction in incidence of diabetes.

iHealth T2D study is one of the world’s largest Diabetes prevention, multi-centre, cluster randomized clinical trial on Type-2 Diabetes (T2D) in south Asian population with central obesity and pre-diabetes. It is funded by the European Union, Horizon 2020 and led by Imperial College London. It brings together an international consortium from the UK, India, Pakistan, and Sri Lanka. Our ambition to develop new approaches to Diabetes prevention that are effective, efficient, locally relevant and sustainable in order to provide evidence about the implementation of lifestyle modifications and health promotion for prevention of Diabetes. The study focuses on primordial and primary prevention and targets people who are in the stage of pre-diabetes and obesity by preventing the onset of diabetes. iHealth T2D study is a 5-year dietary interventional study with 1-year family intervention program running in the following countries (India, Shri Lanka, Pakistan, United Kingdom) with 11 partners where approximately, 20,000 people have been screened between 40-70 years of age who were either pre-diabetic (HbA1c between 6.0-6.4%) or obese with waist more than 100cm.

In India, more than 7000 individuals were screened across the five hubs; Saket (New Delhi), Vaishali (Ghaziabad, U.P.), Gurgaon (Haryana), Muzaffarpur (Bihar) and Mohali (Punjab), and total 912 participants were enrolled into the study. They are now being follow-up for their health status.

Screening in this study was community-based opportunistic screening though health camps. Over a period of two years, more than 100 health camps were organized by Max Healthcare to screen people at all the five hubs in India. These camps were organized in the residential societies, corporate offices, schools (for teaching staff) and even in the religious places including temples, Gurudwaras and Masjids, in order to cover maximum representative population. The iHealth team comprises of one CHW and one hub-coordinator at each of the five hubs, the principal investigator, project manager, study coordinator, team leader of CHWs and a lab technician at the central hub, Saket.

Study Sites In India

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  • Saket(New Delhi)
  • Vaishali(Ghaziabad,UP)
  • Gurgaon(Haryana)
  • Muzzafarpur(Bihar)
  • Mohali(Punjab)

Dietary Intervention

Personalized Dietary consultation, Regular weight monitoring and Hba1c test have proven to be effective in preventing diabetes amongst the screened participants who were at a risk of developing diabetes. Activities like interactive group sessions, food card games and sharing weight reduction targets kept participants motivated towards intervention.

Ihealth Team


Please visit the https://ihealth-t2d.org/ to know more about the study.